RecruitingMigraine
Stimulation of External Carotid Artery Circulation
Eligible age
18–100 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
This study is testing a new approach to help people with migraine headaches. Researchers want to find out if using electrical stimulation to affect blood flow in the external carotid artery is safe and practical for helping control headaches. The goal of the study is to determine whether this approach could improve headache symptoms and overall outcomes for people with migraines.
Sponsor: The University of Texas Medical Branch, Galveston
You may qualify if…
- ✓ Age ≥18
- ✓ Chronic migraine or status migrainosus, or craniofacial pain refractory to maximal medical therapy who are undergoing MMA IA lidocaine infusion.
- ✓ Subject has provided informed consent.
You may not qualify if…
- ✕ Known allergies to lidocaine
- ✕ Seizure disorder, history of seizures, or increased seizure susceptibility
- ✕ Intracranial vascular malformations or dural AVF
- ✕ Hemodynamic instability, any condition where brief hemodynamic shifts may pose risk
- ✕ Previous MMA intervention or craniotomy that could result in MMA occlusion
- ✕ Any implanted electronic device (pacemaker, ICD, DBS, VNS, cochlear implant, spinal cord stimulator)
- ✕ Significant cardiovascular disease (unstable angina, severe arrhythmias, recent MI)
- ✕ Severe autonomic dysfunction
Where it's recruiting
Texas
Galveston
Source: ClinicalTrials.gov · NCT07402954 · last updated 2026-02-20