SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty
Eligible age
65–100 yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
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About this study
This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.
Sponsor: Poznan University of Medical Sciences
You may qualify if…
- ✓ Patients with ASA classification I-III
- ✓ Aged 65-100 years
- ✓ Who will be scheduled for hip arthroplasty under spinal anesthesia
You may not qualify if…
- ✕ Patients who have a history of bleeding diathesis
- ✕ Take anticoagulant therapy
- ✕ History of chronic pain before surgery
- ✕ Multiple trauma
- ✕ patients unable to assess their pain (dementia)
- ✕ patients operated under general anesthesia
- ✕ patients having an infection in the region of the procedure
- ✕ the patient who does not accept the procedure
Source: ClinicalTrials.gov · NCT07449442 · last updated 2026-05-22