AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Eligible age
18+ yrs
Accepts
All genders
Locations
13 states
Healthy volunteers
No
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About this study
This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.
Sponsor: Novo Nordisk A/S
Where it's recruiting
Escondido · Lancaster · Palm Springs
Waterbury
Jacksonville · Naples
Gurnee · Skokie
Louisville
Troy
Springfield
New York
Statesville
Portland
Dallas
Newport News
Source: ClinicalTrials.gov · NCT07509307 · last updated 2026-06-02