Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program
Eligible age
18–39 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The goal of this study is to learn if integrating a chatbot into an existing 12-week smartphone-delivered behavioral weight loss program is feasible and effective for weight loss among young adults. Researchers will compare a standard behavioral weight loss program for young adults that delivers 1-2 brief messages per day (AGILE) to the same program with a chatbot that offers additional behavior change support integrated into the app (AGILE + Chatbot) to determine if the program with the chatbot is feasible, acceptable to participants, and improves program engagement and weight change compared to AGILE alone.
Sponsor: University of North Carolina, Chapel Hill
You may qualify if…
- ✓ body mass index (BMI) of 25-45 kg/m\^2
- ✓ English-speaking and writing
- ✓ own an iPhone with a data plan
- ✓ willing to be randomized to either treatment group
You may not qualify if…
- ✕ Type 1 diabetes or currently receiving medical treatment for Type 2 diabetes
- ✕ Other health problems which may influence the ability to walk for physical activity or be associated with unintentional weight change, including tuberculosis, currently receiving cancer treatment, or history of a heart attack or stroke
- ✕ Report a heart condition, chest pain during periods of activity or rest, or loss of consciousness on the Physical Activity Readiness Questionnaire (PAR-Q; items 1-4), or report any other reason not able to walk for physical activity
- ✕ Lost 10 or more pounds (and kept it off) in the last 6 months
- ✕ Currently taking weight loss medications
- ✕ History of weight loss surgery or planning weight loss surgery in the next 4 months
- ✕ Report a past diagnosis of, or receiving treatment for, a DSM-5-TR (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision) eating disorder (anorexia nervosa or bulimia nervosa)
- ✕ Currently pregnant or planning to become pregnant within the next 4 months
Where it's recruiting
Chapel Hill
Source: ClinicalTrials.gov · NCT07534254 · last updated 2026-04-22