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RecruitingObesityOverweightObstructive Sleep Apnoea

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

Eligible age

18+ yrs

Accepts

All genders

Locations

11 states

Healthy volunteers

No

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About this study

This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with overweight or obesity, and obstructive sleep apnoea treated with positive airway pressure. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it) and which treatment participants get is decided by chance.

Sponsor: Novo Nordisk A/S

Where it's recruiting

Arizona

Gilbert

Florida

Bradenton · Naples · West Palm Beach

Georgia

Atlanta · Lawrenceville

Illinois

Chicago

New York

New York

Ohio

Cincinnati

Texas

DeSoto · El Paso · Houston · San Antonio

Washington

Renton · Seattle

Source: ClinicalTrials.gov · NCT07571109 · last updated 2026-06-09