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RecruitingRFAMicrowave AblationPancreatic Lesion

EUS-Guided Ablation (RFA and MWA) for Pancreatic and Other Gastrointestinal Lesions Registry

Eligible age

18+ yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

This is a single-center, investigator-initiated, prospective observational registry that will collect longitudinal clinical data on adult patients (≥18 years) undergoing endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) or microwave ablation (MWA) for pancreatic and other gastrointestinal/hepatobiliary lesions as part of routine clinical care. The registry will not alter standard-of-care management. Data will be abstracted from the medical record and routine clinical systems. Primary outcomes include change in target lesion size on clinically obtained imaging and overall survival following ablation. Secondary outcomes include changes in tumor biomarkers, adverse events, non-target lesion changes, and patient-reported symptoms.

Sponsor: West Virginia University

You may qualify if…

  • ✓ Adults ≥ 18 years of age.
  • ✓ Diagnosis of a pancreatic premalignant lesion or malignancy, and other gastrointestinal or hepatobiliary lesion for which EUS-guided ablation is planned as part of standard clinical care.
  • ✓ At least one clinically identified target lesion for which RFA or MWA is performed.

You may not qualify if…

  • ✕ In the judgment of the treating clinician, inclusion in the registry would not be appropriate
  • ✕ The individual is expected to be unable to complete routine clinical follow-up.

Where it's recruiting

West Virginia

Morgantown

Source: ClinicalTrials.gov · NCT07625189 · last updated 2026-06-04

EUS-Guided Ablation (RFA and MWA) for Pancreatic and Other Gastrointes · TrialPath