RecruitingRespiratory Syncytial Virus Infections+Metapneumovirus
A Study of Investigational RSV/hMPV Combination and Investigational hMPV Vaccines in Younger and Older Adults
Eligible age
18–80 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
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About this study
The aim of this study is to evaluate the safety, reactogenicity, and immune response of the different formulations of the investigational RSV/hMPV combination vaccine and investigational hMPV vaccine in younger and older adults.
Sponsor: GlaxoSmithKline
You may qualify if…
- ✓ Participants are eligible to be included in the study only if all of the following criteria apply:
- ✓ Written informed consent obtained from the participant prior to performance of any study-specific procedure.
- ✓ Participants who can and will comply with the requirements of the protocol (e.g., completion of the eDiary, return for follow-up visits, ability to access and utilize a phone or other electronic communications).
- ✓ Body Mass Index (BMI) between 18 kg/m\^2 and 33 kg/m\^2, inclusive.
- ✓ Specific inclusion criteria for OA
- ✓ A male or female between and including, 60 to 80 YOA at the time of the study intervention administration.
- ✓ Healthy participants or medically stable patients as established by medical history and physical examination.
- ✓ Specific inclusion criteria for YA
You may not qualify if…
- ✕ Participants are excluded from participating in the study if any of the following criteria apply:
- ✕ History of any reaction or hypersensitivity likely to be exacerbated by any component of the study intervention(s).
- ✕ Any medical condition that in the judgment of the investigator would make IM injection unsafe.
- ✕ Any confirmed or suspected immunosuppressive or immunodeficient condition resulting from disease (e.g., current malignancy, HIV) or immunosuppressive/cytotoxic therapy (e.g., medication used during cancer chemotherapy, organ transplantation, or to treat autoimmune disorders), based on medical history and physical examination (no laboratory testing required).
- ✕ Acute or unstable chronic pulmonary, cardiovascular, hepatic, or renal functional abnormality, as determined by physical examination and medical history.
- ✕ Documented history of HIV, HBV, HCV infection.
- ✕ History of RSV and /or hMPV-associated illness, diagnosed serologically or microbiologically in the last 12 months.
- ✕ Recurrent history or uncontrolled neurological disorders or seizures, or history of demyelinating conditions (including GBS).
Where it's recruiting
Kansas
Lenexa
Washington
Seattle
Source: ClinicalTrials.gov · NCT07628049 · last updated 2026-08-20