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RecruitingMetabolic Dysfunction-Associated Steatohepatitis (MASH)

Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Eligible age

18–75 yrs

Accepts

All genders

Locations

5 states

Healthy volunteers

No

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About this study

This study will test a Regeneron study drug called ALN-CIDEB to find out whether it may help treat a liver disease called MASH. In this study, researchers are looking at the effect of ALN-CIDEB on reducing liver fat, liver injury, and liver scarring. The study will compare ALN-CIDEB with placebo to understand how well ALN-CIDEB works to lower the amount of fat in the liver. The study is looking at: * What side effects ALN-CIDEB might cause * How well ALN-CIDEB works to change liver fat, liver injury, and liver scarring * How the body and the liver change after having ALN-CIDEB, which can help researchers understand why ALN-CIDEB works better for some people than others

Sponsor: Regeneron Pharmaceuticals

Where it's recruiting

Arizona

Tucson

California

Pasadena · Rialto

Florida

Doral · Miami

Louisiana

Marrero · Metairie

Texas

Austin · Georgetown · Houston · San Antonio …

Source: ClinicalTrials.gov · NCT07631637 · last updated 2026-10-26

Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunct · TrialPath