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RecruitingPregnant IndividualsAneuploidyDown Syndrome (Trisomy 21)

The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk Assessment

Eligible age

All ages

Accepts

Women

Locations

6 states

Healthy volunteers

No

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About this study

The goal of the ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) study is to compare the concordance of results of a novel non-invasive circulating fetal cell (CFC) assay to the results of prenatal invasive diagnostic testing or postnatal genetic and clinical diagnosis of the resulting neonate. This is a prospective study of pregnant individuals.

Sponsor: BillionToOne Inc.

You may qualify if…

  • pregnant individuals between 10 and 20 weeks of gestation
  • singleton gestation

You may not qualify if…

  • \- active cancer

Where it's recruiting

Arizona

Phoenix

California

West Covina

Florida

Sarasota

Georgia

Atlanta

Louisiana

Baton Rouge

Texas

Houston

Source: ClinicalTrials.gov · NCT07643896 · last updated 2026-06-12

The ADVANCE (Assay Development and Validation for Pre-Natal and Obstet · TrialPath