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RecruitingOverweightObesity

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

Eligible age

18+ yrs

Accepts

All genders

Locations

16 states

Healthy volunteers

No

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About this study

The purpose of this study is to find out if zenagamtide is safe and effective for treating participants who have excess body weight compared to treatment with semaglutide.

Sponsor: Novo Nordisk A/S

You may qualify if…

  • ✓ Male or female (sex at birth).
  • ✓ Age 18 years or above at the time of signing the informed consent.

You may not qualify if…

  • ✕ Glycated haemoglobin (HbA1c) ≥ 6.5% (48 millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening.
  • ✕ History of type 1 or type 2 diabetes mellitus as declared by the participant or reported in the medical records.
  • ✕ Treatment with glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues within 1 year before screening.

Where it's recruiting

California

Lancaster · Palm Springs · Pomona · San Diego

District of Columbia

Washington D.C.

Florida

Hollywood · Jacksonville · Miami · Miramar …

Georgia

Atlanta · Snellville

Illinois

Chicago · Skokie

Indiana

Indianapolis

Louisiana

Zachary

Missouri

St Louis

New York

Syracuse · West Seneca

North Carolina

Greensboro · Statesville

Pennsylvania

Danville

Source: ClinicalTrials.gov · NCT07668414 · last updated 2026-09-28

A Research Study Investigating How Well the Medicine Zenagamtide Helps · TrialPath