RecruitingOverweightObesity
A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide
Eligible age
18+ yrs
Accepts
All genders
Locations
16 states
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to find out if zenagamtide is safe and effective for treating participants who have excess body weight compared to treatment with semaglutide.
Sponsor: Novo Nordisk A/S
You may qualify if…
- ✓ Male or female (sex at birth).
- ✓ Age 18 years or above at the time of signing the informed consent.
You may not qualify if…
- ✕ Glycated haemoglobin (HbA1c) ≥ 6.5% (48 millimoles per mole \[mmol/mol\]) as measured by the central laboratory at screening.
- ✕ History of type 1 or type 2 diabetes mellitus as declared by the participant or reported in the medical records.
- ✕ Treatment with glucagon-like-peptide-1 (GLP-1) receptor agonists (RA), dual GLP-1/gastric inhibitory peptide (GIP) RAs (or any other GLP-1 based treatment) or amylin analogues within 1 year before screening.
Where it's recruiting
California
Lancaster · Palm Springs · Pomona · San Diego
District of Columbia
Washington D.C.
Florida
Hollywood · Jacksonville · Miami · Miramar …
Georgia
Atlanta · Snellville
Illinois
Chicago · Skokie
Indiana
Indianapolis
Louisiana
Zachary
Missouri
St Louis
New York
Syracuse · West Seneca
North Carolina
Greensboro · Statesville
North Dakota
Fargo
Pennsylvania
Danville
Source: ClinicalTrials.gov · NCT07668414 · last updated 2026-09-28