Digital and Plasma Biomarkers in Delirium
Eligible age
65+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
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About this study
The goal of this observational study is to learn if there are potential digital and plasma-based biomarkers that could help detect, predict, and prognosticate delirium in older adult patients who are admitted to the intensive care unit (ICU). The main question DELTA aims to answer is: Can digital biometrics predict and detect delirium in older adult ICU patients? Do biomarkers of neurodegeneration fluctuate in ICU patients in such a way that delrium could potentially be predicted? Participants admitted o the ICU will wear a digital device to collect biometric data and will have serial plasma samples collected during ICU admission and patients will be also assessed for delirium daily by study staff.
Sponsor: Scripps Health
You may qualify if…
- ✓ Admitted to the intensive care unit
- ✓ Able to consent or have a legally authorized representative consent on their behalf
- ✓ English speaker
- ✓ Expected ICU stay of 48 hours or more
You may not qualify if…
- ✕ Advanced dementia
- ✕ End stage liver disease
- ✕ Renal replacement therapy
- ✕ Structural brain injury, including but not limited to traumatic brain injury, cerebrovascular accident and intracranial hemorrhage,
Where it's recruiting
La Jolla · San Diego
Source: ClinicalTrials.gov · NCT07694206 · last updated 2026-07-09