Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care
Eligible age
0–0.8 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
No
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About this study
Retinopathy of prematurity (ROP) is a disorder of development of the retina and its vasculature that can impact vision in vulnerable preterm neonates for a lifetime. A major barrier to improving ROP outcomes is the lack of easy access and low stress means to obtain objective measures of ROP disease severity across the retina in these infants. The long-term goal of this program is to provide information which will improve preterm infant health and vision via objective bedside imaging and analysis that characterizes retina-wide ROP level of disease, its response to treatment and development, and to rapidly translate this for better early intervention and improved future vision care.
Sponsor: Duke University
You may qualify if…
- ✓ Health care provider, knowledgeable of protocol, agrees that study personnel could contact the Parent/Legal guardian
- ✓ Parent/Legal Guardian is able and willing to consent to study participation for the infant
- ✓ Infant meets the American Association of Pediatrics eligibility of ROP screening, and is age \< 35 weeks postmenstrual age at first visit
- ✓ Infants transferred to nursery for ROP treatment (some participants)
You may not qualify if…
- ✕ Participant or Parent/Legal Guardian unwilling or unable to provide consent
- ✕ Adult participant or infant/child has a health or eye condition that preclude eye examination or retinal imaging (e.g. corneal opacity such as with Peter's anomaly or cataract)
- ✕ Infant has a health condition, other than prematurity, that has a profound impact on brain development (e.g. anencephaly)
Where it's recruiting
Durham
Philadelphia
Source: ClinicalTrials.gov · NCT07738874 · last updated 2026-09-17