Electrical Stimulation Exercise for Individuals With Lower Limb Paralysis
Eligible age
18+ yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this research study is to evaluate the effectiveness of an exercise training intervention (24-36 sessions) to improve muscle strength and endurance in the lower limbs of individuals with paralysis. Specifically, surface electrical stimulation or previously implanted stimulator will be used to stimulate the muscles during various forms of exercise training with the primary focus on improving overall endurance and maximal power output. For this study, peripheral stimulating electrodes will send electrical signals to the muscles enabling the production of coordinated movements for exercise such as cycling or rowing.
Sponsor: Louis Stokes VA Medical Center
You may qualify if…
- ✓ Lower limb paralysis due to SCI or other neurological disorder
- ✓ Greater than 18 years of age
- ✓ Innervated and excitable lower extremity muscles
You may not qualify if…
- ✕ Females that are pregnant
- ✕ Ventilator dependent
- ✕ Current pressure injuries that would be exacerbated by exercise
- ✕ History of spontaneous fractures
- ✕ Cardiovascular or pulmonary disease that would limit the ability to exercise
- ✕ Uncontrolled diabetes or hypertension
- ✕ Large body frame that would prevent participant from comfortably fitting the exercise equipment
- ✕ Any other medical or psychological condition that would be a contraindication to participating in an exercise program
Where it's recruiting
Cleveland
Source: ClinicalTrials.gov · NCT07768761 · last updated 2026-08-17