Redefining Evaluation of Adiposity and Leanness: Broadening Objective Diagnostics for Obesity
Eligible age
18+ yrs
Accepts
All genders
Locations
3 states
Healthy volunteers
No
See if you qualify for this study
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About this study
The purpose of this study is to evaluate body composition across a variety of medical, professional, and commercial devices, including: bioelectrical impedance analysis (BIA) devices, 3-dimensional optical imaging (3DO), manual anthropometry measurements, dual-energy X-ray absorptiometry (DXA), magnetic resonance imaging (MRI), and blood tests. The secondary study purpose is to compare body composition measurements from BIA devices, 3DO, and manual anthropometry measurements within a 1-week period for a subset of the study population. The study plans to enroll 300 healthy (having no life-threatening conditions or diseases; male and female) participants, 18 years of age or older.
Sponsor: Foundation for the National Institutes of Health
You may qualify if…
- ✓ Being willing to provide written informed consent prior to participation Being willing to complete the study visits and comply with the study procedures
- ✓ Being willing to travel to the various study locations for On-site, DXA, MRI, and Phlebotomy visits
- ✓ Being willing to change into appropriate form-fitting clothing for 3DO assessments and/or appropriate gowns for DXA and MRI imaging
- ✓ Must have a BMI within the range of 18.5 - 45 kg/m2
- ✓ Being willing to refrain from all food, drink, and substances for 8 hours prior to the On-site visit(s) and phlebotomy visit
- ✓ Being willing to refrain from all food, drink, and substances for 4 hours prior to the DXA and MRI scan visits
- ✓ Being willing to refrain from any exercise or vigorous physical activity for 24 hours prior to all visits
- ✓ Stable weight (no more than 5 kg change) for 3 months prior to screening
You may not qualify if…
- ✕ Being pregnant or attempting to become pregnant
- ✕ Having medical implants, such as a pacemaker or metal joint replacements, or other metal implants contraindicated for MRI
- ✕ Cosmetic implants, such as breast implants
- ✕ Having a height greater than DXA scanning limit (77 inches)
- ✕ Having a body weight greater than indicated for the equipment (400 lbs)
- ✕ Prior amputation or major body-altering surgery that could invalidate body composition estimates
- ✕ Having claustrophobia or a history of claustrophobia
- ✕ Known HIV infection
Where it's recruiting
Source: ClinicalTrials.gov · NCT07776678 · last updated 2026-08-20