RecruitingOverweight , Obesity
A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)
Eligible age
18–69 yrs
Accepts
All genders
Locations
2 states
Healthy volunteers
Yes
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to learn whether following an online weight loss program with specific dietary and exercise goals (the 30-30-30 plan) can help improve weight loss and other markers of health when compared to an online weight loss program on its own.
Sponsor: Midwest Center for Metabolic and Cardiovascular Research
You may qualify if…
- ✓ Individual is a male or female and 18 to 69 years of age, inclusive.
- ✓ Individual has a self-reported desire to lose weight.
- ✓ Individual has a body mass index (BMI) ≥27.0 and ≤45.0 kg/m2.
- ✓ Individual has calculated energy needs of ≥1800 kcal/d per the Mifflin-St Jeor Equation, with an adjustment for energy expended in physical activity.
- ✓ Individual must be fluent in speaking, reading, and writing in English.
- ✓ Individual owns a Bluetooth-compatible smartphone capable of downloading a fitness tracking app, with a camera, and has reliable Wi-Fi connectivity at home.
- ✓ Individual is judged by the Investigator to be in generally good health on the basis of medical history and screening assessments.
- ✓ Individual is willing and able to undergo the scheduled study procedures, including participating in an interactive, online weight loss program for 6 months, attending virtual meetings, and striving to fulfill dietary and exercise goals.
You may not qualify if…
- ✕ Individual has a laboratory test result of clinical significance based on the judgment of the Principal Investigator or qualified designee.
- ✕ Individual is unwilling or unable to make dietary changes or increase physical activity.
- ✕ Individual is unable to walk ¼ mile unaided without stopping.
- ✕ Individual has a health condition (e.g., chronic pain, orthopedic limitations, heart problems) that would make weight loss or unsupervised exercise unsafe or infeasible. If an individual responds "yes" to any of the questions on the Physical Activity Readiness Questionnaire (PAR-Q) during visit 1, it is up to the Investigator's discretion to determine if unsupervised exercise is safe.
- ✕ Individual habitually consumes \>9 g fiber per 1000 kcal per day based on their responses on the fiber intake questionnaire.
- ✕ Individual habitually engages in ≥210 minutes per week of moderate-intensity or higher physical activity based on their responses on the Stanford 7-Day Physical Activity Recall (Appendix 3).
- ✕ Individual regularly consumes (≥3 times per week) protein supplements, including collagen, within 30 days of visit 1.
- ✕ Individual has a fasting blood glucose ≥126 mg/dL at screening or known type 1 or type 2 diabetes mellitus or use of any hypoglycemic medication (e.g., insulin, sodium glucose cotransporter-2 inhibitors, alpha glucosidase inhibitors, biguanides, thiazolidinediones, dipeptidyl peptidase-4 inhibitors, meglitinides, sulfonylureas, glucagon-like peptide-1 (GLP-1) receptor agonists, and GLP-1/glucose-dependent insulinotropic polypeptide inhibitors), except for metformin, within 30 days of visit 1.
Where it's recruiting
Source: ClinicalTrials.gov · NCT07789769 · last updated 2026-10-05