Sleep Apnea Biomarkers and Adherence to Continuous Positive Airway Pressure
Eligible age
18+ yrs
Accepts
All genders
Locations
0 states
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
Obstructive sleep apnea (OSA) is commonly assessed using the apnea-hypopnea index, although this measure does not fully reflect cardiovascular risk or the physiological impact of the disease. Emerging biomarkers, including sleep apnea-specific hypoxic burden, pulse wave amplitude drop index, and heart rate response, may provide additional information on cardiovascular vulnerability. This prospective multicenter observational study will investigate the association between these biomarkers, measured from the diagnostic sleep study, and adherence to continuous positive airway pressure (CPAP) therapy after three months. Symptoms, quality of life, clinical characteristics, and changes in biomarkers under continuous positive airway pressure will also be evaluated.
Sponsor: Clinique du Millenaire
You may qualify if…
- ✓ Newly diagnosed obstructive sleep apnea with an indication for continuous positive airway pressure therapy
- ✓ Age older than 18 years
- ✓ Written informed consent obtained
You may not qualify if…
- ✕ Continuous positive airway pressure treatment during the preceding 3 months
- ✕ Medical contraindication to continuous positive airway pressure therapy
- ✕ Concomitant condition likely to affect adherence to continuous positive airway pressure, including severe cognitive impairment or an unstable psychiatric disorder
Source: ClinicalTrials.gov · NCT07792746 · last updated 2026-08-28