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RecruitingDiabetes Mellitus, Type 1OverweightObesity

A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabetes Mellitus and Overweight or Obesity

Eligible age

18–70 yrs

Accepts

All genders

Locations

1 state

Healthy volunteers

No

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About this study

The main purpose of this study is to learn more how tirzepatide affects stomach emptying in participants with Type 1 Diabetes Mellitus (T1DM) and overweight or obesity. Participation in this study will last about 8 weeks, including screening and follow-up.

Sponsor: Eli Lilly and Company

You may qualify if…

  • ✓ Have a diagnosis of type 1 diabetes mellitus (T1DM) and have been treated with insulin for at least 1 year prior to screening
  • ✓ Have a body mass index (BMI) greater than or equal to 25.0 kilograms per square meter (kg/m2) at screening
  • ✓ Are of stable weight, that is a self-reported change of 5 kg or less, for at least 90 days prior to screening

You may not qualify if…

  • ✕ Participants who have a known clinically significant gastric emptying abnormality
  • ✕ Have undergone weight loss surgery such as gastric bypass (bariatric) surgery or restrictive bariatric surgery
  • ✕ Have known allergies or intolerance to acetaminophen, tirzepatide, or glucagon-like peptide-1 (GLP-1) receptor agonists

Where it's recruiting

Florida

Miami

Source: ClinicalTrials.gov · NCT07803744 · last updated 2026-09-23

A Study of Tirzepatide (LY3298176) in Participants With Type 1 Diabete · TrialPath