RecruitingCircadian Variation in Anti-Factor Xa (Anti-FXa) Activity
Circadian Variation of Anti-Factor Xa in Hospitalized Trauma Patients
Eligible age
18–80 yrs
Accepts
All genders
Locations
1 state
Healthy volunteers
No
See if you qualify for this study
Answer a few quick questions about your location and health. Takes about a minute.
About this study
The purpose of this study is to determine whether a circadian rhythm exists in anti-FXa levels and AT3 activity in hospitalized trauma patients receiving low-molecular-weight heparin (LMWH) chemoprophylaxis
Sponsor: The University of Texas Health Science Center, Houston
You may qualify if…
- ✓ Inpatient admission for acute traumatic injury ≥72 hours
- ✓ Prescribed LMWH subcutaneous for VTE chemoprophylaxis
You may not qualify if…
- ✕ Pregnancy
- ✕ Brain hemorrhage or non-survivable injury
- ✕ Chronic Kidney disease ≥ 3b estimated Glomerular Filtration Rate (eGFR) less than 30 interferes with coagulation
- ✕ Chronic liver failure
- ✕ -Acute stimulant use of cocaine and methamphetamine
- ✕ Active VTE or ongoing anticoagulation at admission
- ✕ History of coagulopathy or inherited bleeding disorders
- ✕ Chronic alcohol as defined as a documented diagnosis of alcohol use disorder or alcohol consumption exceeding established risk thresholds (men \>14 drinks/week; women \>7 drinks/week) within the prior 3-6 months
Where it's recruiting
Texas
Houston
Source: ClinicalTrials.gov · NCT07856641 · last updated 2026-10-02