RecruitingSARS-CoV-2
A Study to Investigate the Immunogenicity and Safety of mRNA COVID-19 Variant-containing Formulations
Eligible age
12+ yrs
Accepts
All genders
Locations
5 states
Healthy volunteers
Yes
See if you qualify for this study
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About this study
The purpose of this study is to evaluate the immunogenicity and safety of mRNA-1283 and mRNA-1273 (variant formulations) within the current epidemiological environment
Sponsor: ModernaTX, Inc.
You may qualify if…
- ✓ ≥65 years of age at the time of signing the informed consent OR ≥12 to \<65 years of age at the time of signing the informed consent with at least 1 risk factor for severe outcomes from COVID-19.
- ✓ Female participants of childbearing potential may be enrolled in the study if not pregnant or breastfeeding, subject to other criteria specified in the study protocol.
You may not qualify if…
- ✕ History of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection within 6 months prior to enrollment.
- ✕ Acutely ill or febrile within 72 hours prior to or at Day 1.
- ✕ History of a diagnosis or conditions that in the Investigator's opinion could affect participant's safety, assessment of endpoints, assessment of immune response, or adherence to study procedures.
- ✕ Reported history of congenital or acquired immunodeficiency, immunosuppressive condition, asplenia, or recurrent severe infections.
- ✕ History of coagulopathy or bleeding disorder that is considered a contraindication to IM injection or phlebotomy.
- ✕ Receipt of any of the following:
- ✕ COVID-19 vaccine within 6 months prior to enrollment,
- ✕ Any licensed non COVID-19 vaccine within 28 days before or planned receipt within 28 days after the study intervention, except an influenza vaccine, which may be given 14 days before or after receipt of the study intervention,
Where it's recruiting
Source: ClinicalTrials.gov · NCT07863635 · last updated 2026-10-27